The 38-year-old made the plea at a special screening of her inaugural project as a director and writer for the film In the Land of Blood and Honey.
An audience was invited to the event, which took place on Monday (July 31st), at the U.N. University of Tokyo.
She said that her hope was that the film would inspire people to think about and possibly act on the issue of rape in war zones.
Ms Jolie said: "Our aim must be to shatter impunity, so that rape can no longer be used as a weapon of war anywhere in the world as it was in Bosnia, and as it is today from Congo to Syria".
The award-winning film star suggested that initially she hoped she would tell the story of survivors of these atrocities, "but today I am here not only as a director, but as a campaigner, and a part of a global effort that is growing every day".
Written by? Susan Ballion ?
Related news stories:
Angelina Jolie heads to Japan with famous family (26th July 2010)